Tumor Necrosis Factor Inhibitor Drugs Market– Statistics And Analysis & ForecastPosted by Mrudula Karmarkar on December 23rd, 2021 The global tumor necrosis factor inhibitor drugs market size is anticipated to reach USD 42.1 billion by 2026, according to a report published by Grand View Research, Inc. Increasing prevalence of autoimmune diseases, rapid technological advancements, and rise in healthcare expenditure across the globe are some of the major factors expected to drive the growth. Currently, there are five approved TNF inhibitor drugs in the market- Humira (adalimumab), Enbrel (etanercept), Remicade (infliximab), Simponi/Simponi Aria (golimumab), and Cimzia (certolizumab). Biosimilar versions of Humira, Enbrel, and Remicade have been launched, causing a significant paradigm shift in the market. The wave of biosimilars pose a significant internal threat to the biologics sale as biosimilars have a comparable efficiency as the original products. The cost-effectiveness of biosimilars makes them an attractive choice in economically sensitive areas. In addition, emerging countries, such as India, China, and South Korea are active participants in the biosimilar market. Some of the key therapeutic areas involving treatment with TNF inhibitor drugs are rheumatoid arthritis, psoriasis, psoriatic arthritis, Crohn’s disease, and ulcerative colitis. Although these medicines are mostly used for the treatment of autoimmune diseases, several ongoing studies are investigating the role of TNF inhibitors in the treatment of cancer and other inflammatory conditions. Some of the key players in the TNF inhibitor space are involved in strategic initiatives, such as mergers and acquisitions and joint ventures for the co-development of products. In addition, patent infringement issues between the manufacturers makes the market dynamics intensely competitive. For instance, AbbVie resolved an issue with Boehringer Ingelheim, regarding Humira’s intellectual property (IP) rights. As per the terms of the agreement, Boehringer Ingelheim received a non-exclusive license to Humira’s IP in the U.S.- scheduled to begin in July 2023. Have a Query? Ask Our Expert: https://www.grandviewresearch.com/inquiry/5906/ibb The biologics in TNF inhibitor market face a direct internal threat from biosimilars. Loss of patent exclusivities in various regions pave the way for biosimilars. In addition, the market is engaged in an intense competitive rivalry with Interleukin (IL) inhibitors. IL inhibitors have been proven to have improved safety and efficacy profiles and demonstrate superior results in several head-to-head clinical trials. Further key findings from the study suggest:
A significant paradigm shift in the treatment of autoimmune diseases, driven by the targeted action of biologics and the emergence of biosimilars has been observed. However, the consumer demand for cost-effective medicines with improved safety and efficacy profiles is likely to have a positive impact on market dynamics. TNF inhibitors are used to suppress the inflammatory response caused by TNF cytokines and hence are used for the treatment of inflammatory and autoimmune diseases, such as rheumatoid arthritis, psoriasis, Crohn’s disease, and cancer among others. The role of TNF inhibitors in the treatment of metastatic melanomas and locally advanced soft tissue sarcomas is under investigation. Some key players include AbbVie Inc.; Amgen Inc.; Johnson & Johnson Services, Inc.; UCB S.A.; Novartis International AG; Pfizer, Inc.; and Merck & co., Inc. Strategic initiatives including mergers and acquisitions, collaborations, partnerships, and joint ventures, make a competitive market dynamics. Grand View Research has segmented the global tumor necrosis factor inhibitor drugs market on the basis of product, application, sales channel: TNF Inhibitor Drugs Product Outlook (Revenue, USD Million, 2014 - 2026)
TNF Inhibitor Drugs Application Outlook (Revenue, USD Million, 2014 - 2026)
TNF Inhibitor Drugs Sales Channel Outlook (Revenue, USD Million, 2014 - 2026)
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