Articles By freemexy

Published 4 Years Ago
CJ-023423 (CAS 415903-37-6) - LS-H7180
CJ-023423 (CAS 415903-37-6) - LS-H7180 Prostaglandin E2 (PGE2 ) activates four E prostanoid (EP) receptors, EP1-4 . EP4 is a Gs protein-coupled receptor that, by elevating the second messenger cAMP, plays important roles in bone formation and resorption,

Published 4 Years Ago
Carfilzomib [868540-17-4]
Carfilzomib (868540-17-4) is an irreversible proteasome inhibitor with IC50 of <5 nM. IC50: < 5 nM [1] Carfilzomib, an irreversible proteasome inhibitor, has a favorable safety profile and significant anti-tumor activity in patients with relapsed

Published 4 Years Ago
868540-17-4
868540-17-4 PR171 is a novel, orally small-molecule Wnt inhibitor that inhibits TNIK (TRAF2 and NCK-Interacting Kinase). In vitro study has shown that NCM-0846 blocks Wnt signaling and exhibits remarkable anti-tumor and anti-CSC activities. In vivo study

Published 4 Years Ago
CAS № 868540-17-4
CAS № 868540-17-4 Carfilzomib is a second-generation, irreversible, peptide epoxyketone class proteasome inhibitor that targets the chymotrypsin-like β5 subunit of the constitutive 20S proteasome (IC50 = 5.2 nM) and the β5i subunit of the

Published 4 Years Ago
66611-37-8
66611-37-8 Description: 66611-37-8 is a novel poly(ADP-ribose) polymerase inhibitor - protects against nephrotoxicity of cisplatin without compromising its antitumor activity. BGP-15 also inhibits caspase-independent programmed cell death in

Published 4 Years Ago
BGP-15 (CAS 66611-37-8) - LS-H6785
BGP-15 (CAS 66611-37-8) - LS-H6785 The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis. 66611-37-8 is a PARP inhibitor and insulin sensitizer. In perfused heart, it blocks self-ADP-ribosylation of

Published 4 Years Ago
Co-treatment With BGP-15 Exacerbates 5-Fluorouracil-Induced Gastrointestinal Dys
Co-treatment With BGP-15 Exacerbates 5-Fluorouracil-Induced Gastrointestinal Dysfunction Gastrointestinal (GI) side-effects of chemotherapy present a constant impediment to efficient and tolerable treatment of cancer. BGP-15 GI symptoms often lead to dose

Published 4 Years Ago
Lunar Robotic Mission Heracles Will Scout for Human Landings
Lunar Robotic Mission Heracles Will Scout for Human Landings NASA's push to return humans to the moon will get a huge international helping hand. A mission named Heracles will use a robotic rover to survey the lunar terrain in preparation for the

Published 4 Years Ago
Giant robotic arm catches SpaceX's Dragon cargo spacecraft
Giant robotic arm catches SpaceX's Dragon cargo spacecraft Crew members on the International Space Station caught and installed SpaceX's Dragon cargo Monday morning.They helped control a giant robotic arm to catch the spacecraft carrying 5,500 pounds

Published 4 Years Ago
You’re Buying Fancy Jewelry Wrong
You’re Buying Fancy Jewelry Wrong It’s the perfect time to buy something significant for a special person—you know, show them you care. And it’s the perfect time to freak out about how, exactly, to do it. Cheap Jewelry Websites is

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