Fast-Acting Inhalers in Asthma Treatment

Posted by Phil Koln on February 10th, 2021

Bronchial asthma is one of the most common diseases affecting millions of people. It is manifested by wheezing, shortness of breath, a feeling of congestion in the chest, and coughing. When feeling these symptoms, you require immediate help. Many patients use short-acting bronchodilators in the form of inhalations, which, indeed, quickly eliminate attacks and alleviate symptoms, but do not cure the disease itself.

Patients usually find that an emergency inhaler helps control asthma, so they often do not see the need for additional treatment. However, the opposite happens: the number of symptoms and attacks increases, which means that bronchial asthma is not controlled and an exacerbation may develop - a state when emergency inhalers and other conventional therapy no longer help alleviate the patient's condition. The severity of symptoms and the frequency of attacks are rapidly increasing, and the patient is forced to urgently consult a doctor, call an ambulance, and sometimes go to the hospital.

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Thus, the use of an emergency inhaler more than twice a week is an alarming signal and a reason to assess your addiction to it in order to consult a doctor in a timely manner to select the appropriate modern therapy that will reduce the risk of severe exacerbations.

Why is a fast-acting inhaler no longer needed?

Previously, it was believed that the mechanism of bronchial asthma development is based on bronchospasm, therefore, for 50 years, emergency short-range inhalers were the basis of therapy. They quickly relieve symptoms, however, without having an anti-inflammatory effect, they do not act on the main cause and progression of BA - chronic inflammation.

Now experts have come to the conclusion that monotherapy with emergency short-acting inhalers is dangerous for patients with bronchial asthma: the use of more than three emergency short-acting inhalers per year increases the risk of exacerbations of asthma, more than twelve is associated with an increased risk of death from this disease.

Treatment of bronchial asthma: a new approach

Since 2007, the Global Asthma Initiative (GINA) has been actively seeking new treatments for asthma to reduce the risk of associated exacerbations and deaths.

Currently, the medical community has radically revised the principles of treating bronchial asthma: modern therapy should not only eliminate symptoms, but also reduce the risk of exacerbations in the future. Now for the basic therapy of patients with any severity of bronchial asthma, international clinical guidelines recommend prescribing anti-inflammatory drugs, primarily inhaled glucocorticosteroids, using them in monotherapy or in combination with fast-acting bronchodilator drugs of long or short action. For relief of symptoms, it is first of all recommended to use fast-acting bronchodilators in combination with anti-inflammatory bronchodilators.

Today, in the presence of bronchial asthma of any severity, the preferred therapy for arresting attacks is the use of an anti-inflammatory bronchodilator on demand, with or without supportive therapy (depending on the doctor's prescription). Strict adherence to all doctor's recommendations reduces the risk of exacerbations of bronchial asthma.