Top Emerging Trends Of Single-use Bioprocessing Market Progress Forecast 2027

Posted by Mrudula Anil Karmarkar on April 27th, 2021

The global single-use bioprocessing market size is expected to reach USD 33.0 billion by 2027, expanding at a CAGR of 12.8% over the forecast period, according to a new report by Grand View Research, Inc. Owing to the high demand for biopharmaceuticals, suppliers’ product portfolios of disposables have become more robust. Single-use bioprocessing equipment suppliers are working closely with customers to fulfill the growing expectations of customers. Furthermore, significant advancements in bioreactor designing, stirring systems, and film technologies have spurred the revenue in the market.

Biopharmaceutical innovators are at the forefront of the human response to the coronavirus pandemic. A significant number of major biotech firms are in the midst of a race to investigate the Sars-Cov-2 genome and prepare a viable vaccine for the same. As compared to the speed of response to SARS/MERs etc, the biotech entities are investigating SARs-Cov-2 at an unprecedented rate and a considerable amount of funds are being put into the R&D. With multiple candidates in trial, the public and private sectors are anticipated to work in unison for the foreseeable period, until a vaccine is developed for Covid-19. The report will account for Covid19 as a key market contributor.

Increasing demand for disposables consumables has led to several acquisitions, mergers, and partnerships. For instance, Wego Pharmaceuticals is engaged in a partnership with GE Healthcare for the manufacturing of disposables. Similarly, Emergent BioSolutions is working in collaboration with ABEC for the establishment of a Single-use System (SUS)-based dual plant in Maryland. Intelligent biomanufacturing holds great potential in further advancements of single-use manufacturing. Thus, a substantial number of manufacturers are shifting towards automating their workflows which involves the use of SUS. In addition, an increase in the budget of biomanufacturers to incorporate new solutions within their manufacturing plants is anticipated to boost the adoption rate in the market.

One of the key parameters that has resulted in the rapid adoption of SUT-based process lines is flexibility and speed offered by single-use products while keeping total operating expenditure to a minimum. Also, the introduction of automation and intelligent biomanufacturing has boosted the efficiency of SUTs exponentially. With the rising advancements, the penetration of the single-use bioprocessing model is expected to increase substantially.

Single-use Bioprocessing Market Report Highlights

• Simple and peripheral elements dominated the revenue share in 2020 owing to the high usage of transfer systems and bags
• In addition, expanding applications of disposable sensors in upstream biopharmaceutical production has also driven the segment revenue
• Apparatus and plants are expected to grow at a significant growth rate due to the increase in investment in the disposable for downstream applications such as filtration and purification
• Also, constant development in Single-Use Bioreactors (SUBs) with respect to scale and working volume is driving the segment
• Currently, the major application of disposables is in upstream bioprocessing, leading to the large revenue share of this segment
• The high usage rate of SUBs coupled with the continuous introduction of novel products to accelerate upstream processing is anticipated to spur revenue growth in this segment
• Biopharmaceutical manufacturers are estimated as the largest key end-users of this single-use bioprocessing market
• The continuous expansion of single-use manufacturing facilities by contract manufacturing organizations is one of the key drivers for the growth of biopharmaceutical manufacturers
• North America captured the largest revenue share in 2020 as a result of the presence of a substantial number of key biopharmaceutical developers in the region
• Moreover, U.S. encompasses the largest biopharmaceutical market, which has positively influenced the uptake of disposables in this country
• Asia Pacific is expected to be the fastest-growing market, with China and India at the forefront, owing to the continuous expansion of biomanufacturing capabilities in the region
• Domestic players are collaborating with global players for the establishment of joint ventures to drive biologics product in the region
• This is anticipated to increase the use of SUS in Asia Pacific bioprocessing industry
• Key players including GE Healthcare, Sartorius AG, Lonza, and Eppendorf AG dominate the market
• With the wide acceptance of single-use bioprocessing products within the biopharmaceutical industry, these companies continue to supplant their conventional bioprocessing product line with new disposable products

Several end-users have considered Single-use Systems (SUS) as a mainstream approach to achieve maximum productivity and process efficiency. Presence of key OEMs such as GE Healthcare which has been at the forefront of single-use innovation from the introduction of disposable bioreactors and chromatography columns to entire single-use process and biomanufacturing facilities is driving market revenue at a lucrative growth rate.

SUTs have been proven to be robust and scalable from lab/scale-up to cGMP production applications. As per the BioPharm International, nearly 85% of pre-commercial biomanufacturing involves the use of single-use bioprocessing equipment. On the contrary, commercial manufacturing is still dominated by stainless steel-based products. However, with the expanding product line of disposable bioreactors with high working volume, it is expected to witness considerable profit at commercial scale in the coming years.

The market for single-use bioprocessing is anticipated to incorporate big data-based machine learning in the coming years. This would result in the introduction of analytical models that would enable prediction and improvement in process parameters to boost product yields. The growing interest of investors to fund the incorporation of innovative technologies, such as automation and big data, with SUS is anticipated to drive innovations in the space.

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Some key participants in the market for single-use bioprocessing include Meissner Filtration Products, Inc.; Sartorius AG; Eppendorf AG; General Electric Company (GE Healthcare); Corning Incorporated; ThermoFisher Scientific; Rentschler Biopharma SE; Merck KGaA; Pall Corporation; JM BIOCONNECT; Kühner AG; Lonza; Infors AG; Entegris, Inc.; and PBS Biotech, Inc.

The key OEMs in the market for single-use bioprocessing are engaged in offering robust products with a competitive advantage over conventional technologies. Process technologies developed by major manufacturers including Mobius series (Merck), Ready to process- or FlexFactory series (GE Healthcare), FlexAct series (Sartorius Stedim Biotech), and Allegro series (Pall Life Sciences) have been proven to be superior to the stainless-steel equipment.

With the recent expansions in the market, OEMs are now collaborating with independent suppliers to fill technological gaps. Suppliers like PendoTECH are involved in selling a substantial volume of its sensors and monitors to OEMs for GMP production, pilot and toxicology studies, and clinical batches, resulting in revenue growth.

About Grand View Research

Grand View Research, Inc. is a U.S. based market research and consulting company, registered in the State of California and headquartered in San Francisco. The company provides syndicated research reports, customized research reports, and consulting services. To help clients make informed business decisions, we offer market intelligence studies ensuring relevant and fact-based research across a range of industries, from technology to chemicals, materials and healthcare.

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