Find The Best Homocysteine (Hcy) Assay Kit

Posted by Madison Adams on April 13th, 2016

In hospitals, clinics, nursing homes and biological labs, medical practitioners use different types of diagnostic tools to examine signs, symptoms and nature of various diseases. When it comes to diagnosing hyperhomocysteinemia and homocystinuria in patients, Homocysteine (Hcy) Assay kits are widely recommended. People with hyperhomocysteinemia are likely to have an abnormal high level of homocysteine in the blood. Hyperhomocysteinemia can be diagnosed with a homocysteine (Hcy) Assay kit, and can be managed with vitamin B6, vitamin B9 and vitamin B12 supplementation. High level of homocysteine can lead to the below mentioned diseases:

Cardiovascular Risks
Patients with elevated homocysteine are more at the risk of cardiovascular disease and thrombosis. High homocysteine level is also associated with microalbuminuria, which can lead to cardiovascular disease and renal dysfunction.
Neuropsychiatric Illness
Elevated homocysteine levels can cause Alzheimer's disease. In addition to this, low level of vitamin B6 and B12 is risk a factor for mild cognitive impairment and dementia.
Bone Health
Hyperhomocysteinemia increases the risk of bone fractures in elderly people. Homocysteine auto-oxidizes and reacts with reactive oxygen intermediates. This can damage endothelial cells and increase the risk of thrombus formation.

If you are a medical professional, you must be well aware of what Homocysteine (Hcy) Assay kit is and what it’s used for. However if you know nothing about it, you are the right audience to read this article. A Homocysteine (Hcy) Assay is a liquid stable system largely used for in-vitro quantitative determination of total L-homocysteine in serum or plasma. It’s more accurate and reliable than immunochemical method. The assay can be effective in diagnosing the patients with hyperhomocysteinemia and homocystinuria symptoms. Owing to its accuracy, reliability and user-friendliness, the assay kit remains in great demand in hospitals, nursing homes and diagnostic labs. The kit also features excellent correlation with HPLC and Immunochemical methods. It can also be used to diagnose patients with renal diseases because it’s not interfered by the endogenous cystathionine. To put it in simpler terms, the assay has no interference from lipemic and hemolytic substances. The assay can also eliminate the “carry-over” interference with iron or lipase reagents.

Assay Principle
Homocysteine enzymatic assay works on a novel assay principle that assesses the co-substrates conversion product. To free Hcy in the assay, oxidized Hcy is first reduced. Once the Hyc is freed, it reacts with a co-substrate, SAM, and catalyzed by a homocysteine S-methyltransferase. Then the co-substrate conversion product is amplified.

Author’s bio- Author of this article is successfully engaged in offering Homocysteine (Hcy) Assay. For more information:- http://www.diazyme.com

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Madison Adams

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Madison Adams
Joined: November 2nd, 2015
Articles Posted: 20

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