Use Rabbit Anti-Llama Alkaline Phosphatase for Research

Posted by eliteinternet on September 20th, 2021

For any assay-specific target discovery and/or detection, polyclonal antibodies can be quite useful. Of course, all science experiments require excellent data for the results to be worthwhile and later accepted by the scientific community.

For this reason, people are partial to polyclonal antibodies like rabbit anti-llama alkaline phosphatase. The biophysical diversity of polyclonal antibodies allows for a better sense of stability in terms of the environmental challenges that sometimes develop in the processes.

There are some properties that make this material beneficial.

•        Since polyclonal antibodies bind to more than one epitope, they can help deepen the signal from the target protein (even with a low expression level). This makes polyclonal antibodies ideal for immunoprecipitation and chromatin immunoprecipitation.
•        They are tolerant of small variations in antigen. Compared to monoclonal antibodies, polyclonal antibodies are less sensitive to antigen changes like polymorphism, slight denaturation, and heterogeneity of glycosylation.
•        They are highly stable, tolerant of pH or buffer changes.
•        They are low cost and have a short production time.

The multi-epitope binding properties for polyclonal antibodies have clear benefits.

The heterogeneous binding of distinct epitopes and/or antigens, by polyclonal antibodies, renders these reagents more likely to successfully bind to a particular antigen in a variety of different immunoassays and test conditions.

This makes polyclonal antibodies like llama antibodies more suitable for designs than their counterparts.

Polyclonal antibodies generally offer higher sensitivity ranges due to a more effective capturing of multiple antigen variants or epitopes presented by the analytes.

Because polyclonal antibodies often recognize multiple epitopes on a target protein, they are more effective at diagnosing a target for use in chromatin immunoprecipitation.

In immunohistochemistry (IHC), where the effects of the tissue processing and fixation on the epitope are unknown and highly variable, polyclonal antibodies can be a better option because their multi-epitope binding allows for antigen identification.

Furthermore, polyclonal antibodies offer a greater sensitivity for identifying proteins that are present in low quantities in a given sample.

These benefits make it clear. The best place to obtain polyclonal antibodies is from a qualified antibody production facility.