Oligonucleotide Synthesis market trends, top manufacturers, opportunities and forecast to 2027

Posted by kartik joshi on January 5th, 2023

The proposed Oligonucleotide Synthesis market report will encompass all the qualitative & quantitative aspects including the market size, market estimates, growth rates & forecasts & hence will give you a holistic view of the market. The study also includes detailed analysis of market drivers, restraints, technological advancements & competitive landscape along with various micro & macro factors influencing the market dynamics.

The oligonucleotide synthesis market size is estimated to reach US$ 3,971.72 million by 2027 from US$ 1,584.16 million in 2018; it is estimated to grow at a CAGR of 11.1% during 2019–2027.

Synthesis of short fragments of nucleic acids using genetic engineering and enzyme chemistry is called oligonucleotide synthesis. The technique is useful in existing laboratory practice as it provides rapid and inexpensive access to custom-made oligonucleotides of the desired length and sequence. Oligonucleotides are used from initial research and screening to target validation and drug production. Today, subsequent improvements in oligonucleotide synthesis, amplification, and automation have completely revolutionized biological research.

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Furthermore, the Oligonucleotide Synthesis market full research study is designed on account of the fact that each segment is individually assessed and then collated to form the whole market, the study can be tailor-made to fit your exact requirements.

The structure of the Oligonucleotide Synthesis market report can be categorized into following sections:           

Section 1: scope of the report & research methodology

Section 2: key takeaways                                                                    

Section 3: market variables & their impact on growth and analytical tools providing high level insights into the market dynamics and growth pattern

Section 4: market estimates and forecasts (with the base year as 2019, historic information of 2016 & 2018 and forecast from 2021 to 2027). Regional and country level estimates and forecasts for each category which are summed up to form the global market.

Section 5: competitive landscape. Attributes such as strategy framework, competitor categorization are included to provide elaborate details on the market structure & strategic undertakings as well as their impact.

Product-Based Insights

The global oligonucleotide synthesis market, based on product, is segmented into synthesized oligonucleotides, reagents, and equipment. The synthesized oligonucleotide segment is further sub-divided into primers and probes. The synthesized oligonucleotides segment held the largest share among the product segment in the oligonucleotide synthesis market in 2018 and is also anticipated to follow a similar trend over the forecast period.

Synthetic oligonucleotides are being explored for various applications in therapeutics and diagnostics. Oligonucleotides have the property to cause selective inhibition of gene expression by binding to the target DNA/RNA sequences through mechanisms such as antigene, antisense, and RNA interference. These molecules are also known to bind to the target molecules (aptamers), ranging from small molecules to proteins and are, therefore, preferred on a large scale to treat viral diseases and cancer. In addition to diagnostic and therapeutic purpose, oligonucleotides are used for designing DNA microchips that are used as a powerful bio-analytical tool and novel material in the field of nanotechnology. Owing to the benefits offered by synthesized oligonucleotides, the demand for the segment is expected to grow significantly during the forecast period. In 2020, 10 oligonucleotide drugs have received regulatory approval from the FDA

Application-Based Insights

The global oligonucleotide synthesis market, based on application, is segmented into research, diagnostics, and therapeutics. The research segment accounted for the largest share in 2018. The higher emphasis on research activities by countries is expected to spur market growth during the forecast period. For instance, in Canada, there has been an increase in companies’ who are making significant expenses to expand their research and development domain. In both 2018 and 2021, the largest category of R&D spending was around US million to US million. In the field of research, oligonucleotides used for purposes such as gene knockout, genotyping, and diagnosis typically needs further purification after synthesis. Hence, the rise in research activities is expected to offer significant growth opportunities for the concerned market in the coming years.

The prominent/emerging players in the Oligonucleotide Synthesis market research include:

  •          Thermo Fisher Scientific Inc.
  •          GenScript
  •          Molecular Assemblies
  •          Twist Biosciences
  •          Evonetix
  •          DNA Script
  •          Nuclera Nucleics
  •          Camena Bioscience
  •          Synthomics
  •          Ansa Biotechnologies
  •          Helixworks
  •          Iridia
  •          Keasling Laboratories

The Oligonucleotide Synthesis market company profiles are individually represented for all major participants and indices such as financial performance, strategic initiatives, product portfolio & company overview.

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Company overview:

Company overview provides the information about location of the company where it is headquartered along with the established year, employee strength as of 2017, regions where the company is operating and the key business areas.

Financial performance:

Overall company/segment revenue for the year 2019, 2018, and 2017 is provided in the sub title “financial performance” (public listed companies) along with the analysis and explanation of the increase or decrease in the same due to factors such as mergers & acquisition, profit or loss in any strategic business unit (sbus) and others.

Product benchmarking:

Product benchmarking comprises the comprehensive list of products pertaining to the respective market along with the application and key features.

Strategic initiatives:

Insights pertaining to the new product launch, strategic collaboration, mergers and acquisition, regulatory approval, and other developments by the company in market are covered under strategic initiatives section.

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The Oligonucleotide Synthesis market research study is designed keeping in focus all the major countries. Although, all these countries & their market trends were accounted for while composing it, detailed sections are available for only the spearheads. In case if you would be interested in specific countries which are not covered in the current scope, kindly share the list & we can customize the study based on the geographical scope defined by you.

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kartik joshi

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kartik joshi
Joined: September 27th, 2022
Articles Posted: 141

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