Know More About “Preparative And Process Chromatography Market” Growth Worldwide…..

Posted by Mrudula Anil Karmarkar on April 27th, 2023

The global preparative and process chromatography market size is expected to reach USD 17.26 billion by 2028, according to a new report by Grand View Research, Inc. It is expected to expand at a CAGR of 11.65% from 2021 to 2028. High demand for monoclonal antibodies, coupled with the growing adoption of preparative chromatographic techniques in the bioprocessing industry, is anticipated to boost the revenue growth in the market over the forecast period.

Moreover, an increase in the number of R&D activities in the pharmaceutical and biotechnology industries is driving the adoption of liquid chromatographic techniques in downstream assays, resulting in the anticipated market growth. In addition, technological developments to advance the final product recovery in terms of yield accelerate and augment the uptake of these techniques across various applications.

Furthermore, expanding application of these techniques has propelled the key players to make strategic investments to increase their revenue share in the space. Companies are actively engaged in the development of new products to meet the changing consumer demands. For instance, in November 2020, Shimadzu Corporation launched “Advanced i-Series” HPLC. This is an improved flagship liquid chromatography model to support remote work.

Chromatography columns are gaining increasing attention in the global space. Companies involved in prepacked chromatography columns consistently innovate new products to gain a reputed market share. Moreover, the integration of preparative chromatography in COVID-19 vaccine development has created lucrative opportunities for the key players to capture the untapped avenues of the market.

Preparative chromatographic techniques are anticipated to register the fastest CAGR throughout the forecast period due to the increasing application in medical research and the drug approval process. The food end-use segment is estimated to exhibit the fastest CAGR over the forecast period owing to the high use of analytical techniques for food safety and food authentication assessment.

Large-scale integration of liquid chromatographic techniques in downstream processing, technological advancements, and high demand for preparative techniques have accelerated the growth in this space. Increasing demand and approval of monoclonal antibodies in the pharmaceutical and biotechnology industries are expected to fuel the growth in this space throughout the forecast period. This can be attributed to the higher penetration of the service providers in the antibody separation techniques that are based on chromatographic principles, such as affinity chromatography and column displacement chromatography.

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Moreover, ongoing research paradigms for the separation and analysis of monoclonal antibodies using the mild reverse phase chromatography are anticipated to drive research in this market. Companies are engaged in the development of flexible and robust platforms for continuous production of monoclonal antibody products, thereby increasing the demand for quality control.

Preparative And Process Chromatography Market Report Highlights

• By product, process chromatography accounted for the largest revenue share in 2020 owing to the growing research activities and adoption of automated systems in the field of biopharmaceuticals
• On the basis of type, the liquid chromatographic segment dominated the market in 2020 owing to the high demand for preparative HPLC in the therapeutic development process
• Based on end use, the pharmaceutical segment held the largest share in 2020 owing to increasing application in drug safety assessment as an analytical tool for qualitative and quantitative analysis
• North America dominated the market in 2020 owing to increasing investments in the development of new resin for the isolation and purification of vaccines. Extensive COVID-19 vaccine development efforts in the region have spurred the market growth as the process significantly relies on the use of chromatography for the characterization
• Asia Pacific is projected to witness the fastest growth over the forecast period. The growing biopharmaceutical sector in the region has increased the demand for antibodies and resins. Extensive R&D activities in the Asian pharmaceutical market result in the growing demand for chromatography products

Affinity chromatography has emerged as a pivotal tool to purify proteins as it is based on highly specific interactions occurring between the protein of interest and an immobilized ligand. The Downstream Process (DSP) or the product purification process is one of the costliest aspects of modern bioprocess protocols, particularly with respect to proteins. Hence, in these cases, chromatography serves as a crucial tool at all stages of DSP, from early initial capture to the final polishing or finishing steps.

Preparative techniques have gained wide acceptance for the purification of APIs and the key drivers associated with this expanding acceptance include improved throughput, cost-effectiveness, and purity. These techniques offer the users sufficient material volume at the desired quality for the initiation of clinical and preclinical trials. This, in turn, opens alternative routes for commercialization with minimum time invested in product development.

List of Key Players of Preparative And Process Chromatography Market

• GE Healthcare
• Agilent Technologies
• Danaher Corporation
• Bio-Rad Laboratories Inc.
• Merck KGaA
• Thermo Fisher Scientific Inc.
• Shimadzu Corporation
• Novasep Holding S.A.S
• Waters Corporation