Top Emerging Trends Of Scaffold Technology Market Progress Forecast 2025 |Grand View Research, Inc.

Posted by Mrudula Anil Karmarkar on May 2nd, 2023

The global scaffold technology market size is expected to reach USD 2.1 billion by 2028, according to a new report by Grand View Research, Inc. The market is expected to expand at a CAGR of 8.4% from 2021 to 2028. The market growth can be primarily attributed to the growing popularity of bioprinting for mimicking the tissue microenvironment in printed 3D tissue models. The need to expand the horizon of multidisciplinary research areas has supplemented the adoption of scaffold technologies in 3D printed models.

For instance, in October 2021, researchers integrated novel biomaterial scaffold-guided regeneration for multiple periodontal tissues. The incorporation of advanced imaging modalities along with 3D printing has facilitated non-invasive tracking of in vivo degradation of scaffolds. The advent of such technologies is expected to propel the adoption of scaffolds in tissue engineering and regeneration, thereby providing considerable momentum to market growth.

Additionally, the development of novel diagnostic and therapeutic strategies such as tissue engineering, regenerative medicine, have been largely favored in the wake of the pandemic outbreak of SARS-COV-2 infection. Expanding research activities in the field of tissue engineering have led to the advent of scaffold-based vaccine systems, which have the potential tocombatCOVID-19. Progress in this area is expected to cause a surge in the adoption of advanced medical technologies in COVID-19 vaccine development and research.

Furthermore, researchers are proactively using in vitro human lung tissue models developed using tissue-engineered for the understanding of mechanisms of the infection and host-pathogen interface. The application of tissue engineering is used for culturing multiple pulmonary cell lines, improving the relevance of in vitro models, and the use of 3D scaffolds that mimic native pulmonary architecture.

The growth of the market can be primarily attributed to the rising demand for 3D cellular models in biological studies and translational research. The rapid shift in the cell culture paradigm to overcome the challenges associated with the drug development process is expected to propel the growth of the market for scaffold technology.

The application of 3D cell cultures is growing as they are efficient in mimicking the in vivo physiological state for efficient representation of disease-causing micro environmental factors. Thus, 3D cell culture techniques have emerged as a novel tool for early drug discovery as well as potential therapeutic solutions for the treatment of various diseases. The 3D concept of cell cultivation allows the investigation of phenotypic heterogeneity of cancer cells and heterotypic crosstalk between cells by providing relevant information about diseased cells, thus driving the market.

In addition, the significant advancements in regenerative medicine and tissue engineering in recent years have increased the adoption of 3D bioprinting for organs and tissues reconstruction procedures. 3D bioprinting technique is considered to be one of the most profitable advancements in the field of regenerative medicine; wherein the biological material is directly printed onto scaffolds that could require cell seeding.

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Companies are developing new 3D bioprinted personalized scaffolds for tissue regeneration. For instance, in November 2020, CELLINK GLOBAL entered into a TRIANKLE consortium for developing new personalized gelatine and collagen-based implants with the application of 3D printing technology for ankle joints tissue regeneration. Hence, the integration of new technologies for the tissue reconstruction process is further driving the market for scaffold technology.

Moreover, the COVID-19 pandemic is acting as a positive catalyst for the market for scaffold technology. The application of tissue engineering is extensively used for understanding virology and epidemiology, developing in vitro model systems, and finding efficient therapeutic solutions for dealing with the infection. Companies are developing new scaffolds for combating the COVID-19.

Scaffold Technology Market Report Highlights

  • The hydrogels segment dominated the market in terms of revenue in 2020 owing to advantages such as high biocompatibility, thermal reversibility, and strong cellular activities, contributing to its increasing adoption rate
  • The nanofiber-based scaffolds segment is expected to witness lucrative growth owing to the growing advancements such as 3D molding for developing 3D nanofiber membranes
  • The stem cell therapy, regenerative medicine, and tissue engineering segment held the largest revenue share in 2020
  • This growth is attributed to the expanding adoption of scaffolds in the aesthetic procedure, wound healing, periodontology, and colorectal surgeries
  • The drug discovery segment is expected to witness the fastest CAGR over the forecast period
  • Scaffolds play a vital role in the elucidation of molecular reasons for the activity of drug candidate in toxicity screening procedures, which is expected to impact the growth of medical technology in this segment
  • The orthopedics, musculoskeletal, and spine segment held a substantial market share in 2020 due to an increase in the popularity of regenerative medicines
  • Regenerative medicines can offer various lower risk substitutes to allograft surgery, thereby supplementing the adoption of the technology in this segment
  • The biotechnology and pharmaceutical industries segment dominated the market in terms of revenue share in 2020 owing to their high engagement in new drug discovery and development
  • North America held the largest revenue share in 2020. Growth in this region is owing to the presence of key players and extensive R&D activities
  • Companies operating in the market are entering into partnership for developing 3D cell culture models
  • For instance, in March 2021, PELOBiotech GmbH entered in partnership with Rigenerand SRL for developing 3D Cell Culture models. The company distributed its VITVO handheld bioreactor which is integrated with a scaffold for establishing in vitro 3D cell culture model that is used in pre-clinical investigations and research applications

For instance, in April 2020, Ligandal developed a peptide scaffold as a prospective antidote and vaccine for COVID-19. The scaffold is designed using AI and supercomputing that mimics the immune binding and attaching elements of the virus. Hence, such synthetic constructs with the advantages such as rapid prototyping and efficient scale-up can offer therapeutic solutions for SARS-CoV-2.

The stem cell therapy, regenerative medicine, and tissue engineering segment dominated the market for scaffold technology and accounted for the largest revenue share of more than 66.0% in 2020.The growth is attributed to the growing implementation of scaffold technology for reconstruction surgeries, aesthetic surgeries, soft tissue tumor repair, abdominal wall repair, periodontology, and colorectal surgeries.

In addition, the extensive application of scaffold technology across the field of regenerative medicine is gaining significant traction among researchers in recent years. For instance, in November 2020, scientists from Wake Forest Institute for Regenerative Medicine scientists (WFIRM) developed a hybrid tissue construct that can be used for cartilage regeneration. It is developed with the application of 3D bioprinting technology. Hence, the growing research for the development of tissue can be further attributed to segment growth.

List of Key Players of Scaffold Technology Market

  • Merck KGaA
  • Thermo Fisher Scientific, Inc.
  • Becton, Dickinson, and Company
  • 3D Biotek LLC
  • Xanofi
  • Molecular Matrix, Inc.
  • Tecan Trading AG
  • REPROCELL Inc.
  • Matricel GmbH
  • Pelobiotech
  • Corning Incorporated
  • Akron Biotech
  • Avacta Life Sciences Limited.
  • Nanofiber Solutions
  • 4titude
  • Bioquote Ltd
  • Vericel Corporation
  • NuVasive, Inc.
  • Allergan
  • Medtronic

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Mrudula Anil Karmarkar

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Mrudula Anil Karmarkar
Joined: July 2nd, 2020
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