How Modafinil Works

Posted by Jennifer Brown on June 5th, 2024

Modafinil, renowned for its cognitive enhancement and wakefulness-promoting properties, functions by influencing various neurotransmitters in the brain, including dopamine, serotonin, orexin, and others. Developed by Michel Jouvet and Lafon Laboratories, Modafinil, also known as a eugeroic, is commonly prescribed to treat conditions like narcolepsy, shift work sleep disorder, and obstructive sleep apnea. Its mechanism of action involves altering neurotransmitter levels in brain regions responsible for regulating the sleep-wake cycle. Despite being a Schedule IV controlled substance approved by the FDA in 1998, Modafinil's off-label uses extend to enhancing cognitive function, treating fatigue associated with conditions like cancer and multiple sclerosis, and aiding in cocaine addiction therapy. The drug's half-life ranges from 10 to 12 hours, with effects lasting up to 12 hours, making it popular among individuals seeking sustained wakefulness and improved cognitive performance. However, due to its potent effects, it's crucial for individuals to consult healthcare professionals before use to ensure safe and appropriate administration.

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