Single-Use Bioreactor Market, Trends, Innovation, Drivers, Analysis by 2024

Posted by Yash Chauhan on March 1st, 2019

The global single-use bioreactor market is growing at a significant pace due to increasing biologic market, patent expiry of products and reduced automation complexity. The market has observed high demand for single-use bioreactor systems over the last couple of years, due to its advantages such as the elimination of validation issues and shortened downtime.

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Globally market has been segmented by product into single-use bioreactor system, media bags, filtration assemblies, and others. SUB system account for the biggest share in the market, due to increasing adoption of SUB systems by pharmaceutical firms and its advantages such as reduced downtime and elimination of validation issues. Furthermore, it decreased the risk of cross-contamination due to use of new bags for each run.

The global single-use bioreactor market has also been divided by type of cell into the bacterial cell, a yeast cell, a mammalian cell, and others. The mammalian cell segment is estimated to account major share and is expected to grow at the fastest pace in the market due to the rising application of mammalian cell in biologics manufacturing due to its high therapeutic efficiency.

The different kinds of molecule single-use bioreactor market are further segmented into vaccines, gene-modified cells, monoclonal antibodies, stem cell, and other molecules. The monoclonal antibodies are estimated to account the biggest share in the market due to growth in demand for SUB system which provides greater productivity and flexibility, less requirement of manpower and low investment cost.
The single-use bioreactor market has also been further segmented by application into research and development, bioproduction process and process development. The bioproduction process segment is estimated to account the biggest share in the market due to increasing adoption of SUB system due to its easy implementation and low investment cost.

Different type of end-users in the single-use bioreactor market are biopharmaceutical manufacturer and R&D departments. Biopharmaceutical manufacturer accounts the bigger share in the market due to the increasing number of SUB products in biopharmaceutical companies.

Growth Drivers

The increasing use of SUB among small firms reduced environmental impact, and patent expiry of products are the primary growth drivers for single-use bioreactor market. The use of SUB provides immense flexibility to pharmaceutical firms. It helps pharmaceutical companies in time-saving, reduces the energy efficiency and complexity of automation.

However, increasing the biologics market, reduced automation complexity, and ease in the cultivation of marine organisms are also fueling the growth of the global single-use bioreactor market. Automation of stainless-steel system and single-use systems differ in complexity. Stainless-steel reactors need continuous cleaning and sterilization which results in high consumption of chemicals and ultrapure water.


The current need for improved single-use sensors, regulatory concerns related to SUB, standardization of single-use designs and issues regarding leachable and extractable are the huge challenges for the growth of single-use bioreactor market.

Industry Ecosystem

All manufacturers are guaranteeing that products bring about cost savings in biopharmaceutical firms. Manufacturers are focused on improving mixing; reduce complexity, and avoiding leakage, and other integrity issues, which help them to retain their market share worldwide.

Geographic Overview

Globally, Europe is the largest single-use bioreactor market as the government in the region supports for new biologics. Few of the other factors leading to the growth of the European market are growing research activities, reduced environmental impact, technological advancement, patent expiry of products, and growing adoption of SUB systems.

Asia-Pacific especially China, Japan, India is observed to witness the fastest growth in the market. growing biologics market and increasing use of SUB in small and startup companies are the primary factors boosting the growth of the market. However, increasing research activities and reduced automation complexity are also driving the growth of the Asia-Pacific market.

Competitive Insight

Main players in the industry are mainly investing in the development of innovative and advanced products, which is strengthening their position in the global market. On March 2018, WuXi Biologics announced that it has selected ABEC’s Custom Single Run disposable bioreactors for its new commercial manufacturing facility in Wuxi city, China. Sartorius Stedim Biotech, Eppendorf, Merck Millipore, Cesco Bioengineering, GE Healthcare, Applikon Biotechnology, Danaher, Thermo Fisher Scientific, Parker Hannifin, Cellexus and Celltainer Biotech are some of the key players offering single-use bioreactor.

​​Source: VynZ Research

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Yash Chauhan

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Yash Chauhan
Joined: February 25th, 2019
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