Multiplexed Diagnostic Market : Focus on Screening, Monitoring

Posted by Pareesh on April 22nd, 2019

Multiplexed diagnostics are used in investigation of biological samples, which are capable of completing a screening process with a single run. Multiplexed diagnostic assays are involved in the detection and diagnosis of different diseases and infections, which include cancers, autoimmune diseases, allergies, and cardiovascular diseases. Assays performed in multiplex diagnostics include high density multiplexed assays, medium density multiplexed assays, low density multiplexed assays, and next-generation sequencing assays. Early diagnosis can minimize the risk factors associated with chronic diseases/infection and helps in proper treatment management. Moreover, multiplexed diagnostic assays have advantages, such as time efficiency and highly precise accuracy, which can analyze defects and mutations in any functional biomolecules (DNA, RNA, and protein).

According to the Centers for Disease Control and Prevention (CDC), 2014, around 236,968 women are diagnosed with breast cancer. Increasing demand for early diagnosis of infection/diseases needs rapid multiplexed diagnostic tools, which is expected to boost the growth of the multiplexed diagnostic market.

The global multiplexed diagnostic market is estimated to be valued at US$ 8,698.0 in 2017 and is expected to witness a CAGR of 7.9% during the forecast period (2017 – 2025).

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According to Cancer Research UK, around 20 cases of ovarian cancers are diagnosed every day and it is projected to increase by around 15% from 2014 to 2035. Furthermore, according to American Cancer Society (ACS), in 2017, approximately 53,670 people are expected to be diagnosed with pancreatic cancer in the U.S. Moreover, according to Cancer Research UK, approximately 3,072 new cases were diagnosed with acute myeloid leukemia (AML) in 2014.  As per Cancer Research U.K, Acute Myeloid Leukemia (AML) accounts approximately 8 cases per day. Increasing incidence of multiple cancers is expected to increase the demand for precise multiplexed diagnostic tools, in turn fueling the market growth.

Additionally, SpeeDx has received CE-IVD marking for its PlexPCR VHS Multiplex qPCR technology in October 2017. This diagnostic test is designed to detect and differentiate the four different genital and oral lesion viruses, which include herpes simplex virus types 1 and 2 (HSV-1 and -2), varicella-zoster virus (VZV), and Treponema pallidum (syphilis). Therefore, PlexPCR VHS Multiplex qPCR test is expected to provide early detection of infection and help in treatment decisions. Thus, advanced technology is expected to boost the growth of multiplexed diagnostic market during the forecast period.

Introduction of advanced technology in multiplexed diagnostic tools, create a positive impact on patient and is expected to fuel the growth of the multiplexed diagnostic market

Mercodia has launched the AKURIO Islet Hormone multiplex assay with the collaboration of Quansys Bioscience in October 2017. This assay is designed to assess four different hormones in pancreatic study, which include glucagon, insulin, C-peptide, and proinsulin. AKURIO Islet Hormone multiplex assay provides high data accuracy with reliable speed. Moreover, Bruker has received CE-IVD marking for its Fungiplex Candida diagnostic assay in October 2017. Fungiplex Candida is based on real-time PCR and gives results in 2-3 hours of blood, plasma or serum sample by cutting the edge of additional cultural steps. Thereby, establishment of rapid detection assay in fungal infection allows the development of effective treatment strategies for improved patient outcomes.

The multiplexed diagnostic market is gaining significant traction due to the rising prevalence of autoimmune diseases. According to the Centers for Disease Control and Prevention (CDC), the prevalence of arthritis from 2013 to 2015, was estimated in 54 million U.S adults (22.7%) and by 2040, it is expected to be 78 million (26%) U.S adults age 18 years or older. The data represent the high prevalence of autoimmune diseases, indicating the need of advance diagnostic measures, which is expected to boost the growth of the multiplexed diagnostic market. Furthermore, introduction of technological advancement of multiplexed diagnostics is a major factor contributing to the market growth. For instance, IQuity launched RNA-based diagnostic test based on RT-PCR assay approved by U.S. Food and Drug Administration (FDA) in May 2017. RNA-based diagnostic test is used for detection of multiple sclerosis, which provides accuracy by 90%. However, the high cost of diagnostic procedures is a major restraining factor for the multiplexed diagnostic market.

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Pareesh

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Pareesh
Joined: May 31st, 2017
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