Cell Free Protein Expression Market Applications and Competitive Outlook To 2025

Posted by Rajkumar on May 27th, 2019

Cell free protein expression is also called as cell-free protein synthesis, in vitro translation, cell-free translation or in vitro protein expression. It is a well-developed, rapid, and efficient technique for synthesizing proteins in cell lysates rather than cultured cells. Cell free protein expression uses translation machineries to extract the desired cells. It can be done by using various types of mammalian cells, bacteria, plants, and insect cells over conventional in vivo method. For instance, cell free protein expression system works independently and is free of any cellular context, owing to these benefits it is ideal for high-throughput screening of mutagenesis. Moreover, the whole machinery of cell free expression system sets better environment to manufacture membrane proteins, toxic proteins, and proteins that can undergo degradation. Pharmaceutical and biotechnological industries actively utilize these tools for research and developmental activities as well as for genomics and proteomics. Thus, it is a key factor propelling the cell free protein expression market growth over the forecast period.


The global cell free protein expression market sizewas valued at US$ 177.1 million in 2017, and is expected to witness a CAGR of 6.2% over the forecast period (2018 – 2026).


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Robust research and development is expected to drive growth of the cell free protein expression market


Increasing research and development in the field of proteomics and genomics and high prevalence of infectious disease and cancer are the major factors driving growth of the cell free protein expression market. For instance, According to 2012, EU Industrial R&D Investment Scoreboard, the pharmaceutical and biotechnology sectors represented 17.7% of business R&D expenditure in the world. Moreover, high prevalence of infectious disease and cancer cases across the world are resulting into high adoption of cell samples for research and development of drugs thus, expected to have a meteoric growth for the cell free protein expression market. For instance, According to the estimates by GLOBOCAN 2012, an estimated 850,000 new cancer cases were diagnosed in Africa, while almost 600,000 deaths were attributed to malignant disease. The number of cancer cases is expected to rise to 1,056,000 by 2020.


Cell Free Protein Expression Market- Regional Analysis


Cell free protein expression market is segmented into six major regions- North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. Increasing cell-based research in North America due to high demand for precision medicine is a major factor driving growth of the cell free protein expression market in this region. In 2015, the Precision Medicine Initiative was launched in the U.S. to revolutionize the treatment of diseases, which include cancer and other chronic diseases, as precision medicine offers tailored treatment for an individual according to genetic makeup of the person. Furthermore, increasing emphasis on proteomics and genomics research activities in UK, Germany, France, and Switzerland are fueling growth of the European cell free protein expression market.


Cell Free Protein Expression Market- Competitive Landscape


Key players operating in cell free protein expression market include iBio CDMO LLC, Thermo Fisher Scientific Inc., Takara Bio, Inc., New England Biolabs, Promega Corporation, CellFree Sciences Co., Ltd., Biotechrabbit GmbH, Bioneer Corporation, Cube Biotech GmbH, Jena Bioscience GmbH, and GeneCopoeia, Inc.


Detailed Segmentation:


Global Cell Free Protein Expression Market, By Application:

  • Therapeutic Application

  • Research Application


Global Cell Free Protein Expression Market, By Product Type:

  • Expression Systems

  • Prokaryotic Expression Systems

  • Mammalian Cell Expression Systems

  • Insect Cell Expression Systems

  • Yeast Cell Expression Systems

  • Other Systems

  • Consumables and Other Products


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Joined: February 13th, 2019
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