Information of Terlipressin Acetate

Posted by freemexy on September 5th, 2019

Information of Terlipressin Acetate

Terlipressin Acetate powder,Terlipressin powder (trade names Teripress by New Medicon Pharma and Glypressin by Ferring Pharmaceuticals) is an analogue of vasopressin used as a vasoactive drug in the management of hypotension. It has been found to be effective when norepinephrine does not help.
Indications for use include norepinephrine-resistant septic shock and hepatorenal syndrome. In addition, it is used in bleeding esophageal varices.
Item Name Terlipressin Acetate
Cas No. 14636-12-5
Molecular Formula C52H74N16O15S2
Molecular Weight 1227.37
Information of Terlipressin Acetate:
Purity (HPLC) 98.0%min.
Appearance White powder
Single Impurity (HPLC) 1.0%max
Amino Acid Composition ±10% of theoretical
Peptide Content (N%) ≥80.0%
Water Content(Karl Fischer) ≤10.0%
Specific Rotation (20/D) -95.0~-105.0°(c=1 1%HAc)
Acetate Content (HPIC) ≤15.0%
MS(ESI) Consistent
Mass Balance 95.0~105.0%

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freemexy
Joined: December 6th, 2018
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