Principle of Selection of ExcipientsPosted by Elleder on September 12th, 2019 Capsule pills, tablets, etc. need to add the excipients during the manufacturing process. Sometimes the amount of excipients even are greater than the main drug. In the preparation of the capsule drug, in addition to the main drug powder, an additional agent such as a diluent, a lubricant, a disintegrator or the like are added as needed. These add-on agents together with the drug affect the disintegration of the capsule and the release of the main drug. Excipients are the basis of raw material, and also have an important impact on the pill making process, stability, safety, product quality and efficacy of the capsules. Picture by Marco Verch from flickr In the selection of excipients, the following principles need to be followed:
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