A Call to Revolutionize Chronic Pain

Posted by Jessymeshak on December 20th, 2019

For example, if you were crossing the road Projoint Plus Review  and trod on a nail you would expect this to hurt nail into foot, tissue damage, brain receives danger signals from foot via spinal cord and responds with pain to motivate a limp, shout etc. However, if you were to tread on the nail and a bus was careering towards you, the foot would be the least of your worries.

With an acute injury such as an ankle sprain or a wound, the damaged tissue releases various chemicals that sensitise the nerves. These nerves are usually quiet and only respond when excited by certain chemicals; i.e. their threshold for firing signals is lowered. These nerves send 'danger' signals when excited to the spinal cord where they communicate with further nerves called secondary neurons.

The bombardment of signals causes sensitivity to develop within the spinal cord meaning that subsequent signals are amplified. To us that will mean that in this sensitised state a painful stimulus applied to the affected area will be more painful and a non-painful stimulus light touch, pressure would be painful. Think of a hot shower with sunburn or pressing a bruise.

The signal is then sent from the spinal cord up to the brain where it is scrutinised in the light of past experience, genetics, gender, beliefs, expectations, understanding, emotions and other factors. The brain then creates an appropriate response to the perceived situation and if indeed there is the conclusion that the tissues are in danger, then the 'output' from the brain will be pain.

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