Cholesterol Whey and LDL

Posted by NutriOxDistribution on November 25th, 2020

The positive health benefits of whey protein concentrate do not end with its effects on immunity and cancer prevention and treatment. Whey protein concentrate was also found to be a potent inhibitor of low density oxidised lipoprotein cholesterol. Current research suggests that LDL conversion to oxidised LDL is the trigger that leads to atherogenesis... Plaque formation and lesions associated with atherosclerosis.

Any substance that prevents oxidation of LDL is therefore thought to be anti-atherogenic. Although animal-based proteins have traditionally been involved as pro-atherogenic, whey proteins appear to be an exception to the rule. Wey protein consists of several minor and major fractions, such as beta-lactoglobulin, alpha-lactalbumin, albumin, lactoferrin and immunoglobulin. The minor constituent responsible for the ability of whey protein concentrate to prevent oxidation of LDL appears to be the lactoferrin fraction of the protein.

3. In Whey, Lactoferrin

When lactoferrin was removed from the protein, the ability of whey protein concentrate to prevent LDL oxidation was significantly reduced, leading researchers to speculate, "Our results suggest that LF (lactoferrin) is the main factor responsible for the inhibitory effect of whey protein (LDL) and may function synergistically with other whey protein factors, such as whey protein.

Another study using rats examined the effects of whey protein concentrate and casein on cholesterol and risk factors for heart disease. Although casein (another milk-based protein commonly used in research) is known to increase cholesterol in humans and animals, whey protein has the opposite effect, leading researchers to note, "At the high dietary protein level [300 gramme per kilogramme of feed] , whey protein significantly lowered plasma and liver cholesterol and also plasma triacylglycerols."

4. The cholesterol-lowering effects of whey protein concentrate in this study were also associated with a reduction in LDL cholesterol. Most interesting was the fact that this effect on cholesterol was not seen when the animals were fed amino acid mixtures that simulated whey protein, so it is clear that there are properties within the whey that have these effects beyond the amino acid profile of the animal.

Way and Bone Growth

Finally, protein whey appears to play a direct role in bone growth. Researchers found that rats fed whey protein concentrate had increased bone strength and bone protein, such as collagen. This discovery led research to test whether or not the whey protein directly stimulated osteoblast (bone cell) growth in vitro.

Whey proteins have been shown to stimulate, dose-dependent, total protein synthesis, DNA content, and increased bone cell hydroxyproline content.

5. It should be noted that not all protein concentrates are equal. The manufacturer takes special care to process whey proteins to remove lactose and fats without losing their biological activity. The protein must be processed under low temperature and low acidic conditions so as not to "denature" the protein. Maintaining the natural state of the protein is essential for the biological activity of the protein. These research findings, combined with the previous decade of the whey protein study, should convince anyone that whey protein concentrate is truly a life-long protein.

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