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CD Genomics is aiming at providing the research community wi
Joined: November 27th, 2018
Articles Posted: 145

Articles

Published 21 Days Ago
Unraveling Gene Transcription: Exploring Chromatin Accessibility with ATAC-Seq
Gene transcription requires the unraveling of a higher structural part of the DNA. This part of the chromatin is called accessible chromatin region and this process is achieved mainly by the modification of chromosomal histones (especially acetylation).

Published 21 Days Ago
Long-read Sequencing Reveals Unseen Genomic Variants
A complete map of genomic variation is important to gain insight into genetic characterization and to aid in precision disease research, which can further address research areas such as evolution, agriculture, and medicine. Although short-read long sequen

Published 21 Days Ago
Introduction to the Complete Sequence of a Human Genome
The first essentially complete human genome sequence was released in 2013 as part of the Human Genome Project, which took the use of state-of-the-art DNA sequencing technology and pushed it to its absolute limits.

Published 21 Days Ago
Basics of BLAST: A Sequencing Alignment Tool
The BLAST algorithm has been fine-tuned to find these domains or shorter sequence similarity stretches. An mRNA can also be associated with a piece of genomic DNA using the local alignment method, which is usually utilized in genome assembly and analysis

Published 21 Days Ago
FASTQ: A Processing Tool for Data Analysis
A FASTQ file is a text file that stores the sequence data from clusters that pass the flow cell's filter. Demultiplexing is the first phase in creating a FASTQ file if specimens were multiplexed.

Published 21 Days Ago
Exploring the Advantages of Low-Pass Whole Genome Sequencing
Low-pass whole genome sequencing refers to shallow whole genome sequencing, the process of sequencing an individual's genome at a lower depth, typically around 0.1x to 5x coverage, as compared to the standard depth of 30x to 50x in traditional whole genom

Published 21 Days Ago
Integrative Approaches in Pangenome Analysis for Genetic Understanding
During the long evolution of species, each individual has developed extremely specific genetic traits as a result of natural and anthropogenic selection, among other factors. In the classical view of intraspecific genetic variation, the genome of each ind

Published 21 Days Ago
Next-Generation Sequencing (NGS) Revolutionizes Pathogen Detection
Despite a multitude of microorganisms known to inflict human infections, prevailing diagnostic techniques merely scratch the surface, leaving a vast array of pathogens unidentified. This persistent challenge is further exacerbated by the continuous emerge

Published 1 Month Ago
Copy Number Variation Analysis
Currently, SNP arrays, short-read, and long-read-length genome sequencing are genome-wide high-throughput technologies that can be used to analyze CNVs in an individual's genome. Each of these technologies has its own limitations and advantages. Among the

Published 1 Month Ago
Principles and Key Concepts of Bioinformatics Experimental Design
A good experimental layout is essential for bioinformatics and data analysis. To begin, one must first evaluate the question that high throughput sequencing data is being used to answer. An experiment that is guided by a hypothesis will always be more inf

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