kiko

kiko

CD Genomics is aiming at providing the research community wi
Joined: November 27th, 2018
Articles Posted: 151

Articles

Published 19 Days Ago
What Is Small Nucleolar RNAs (snoRNA) and How to Study It?
New evidence suggests that snoRNAs have a role in a variety of physiological and pathological cellular processes. snoRNA mutations and abnormal expression have been found in cell transformation, carcinogenesis, and metastasis, suggesting that snoRNAs coul

Published 19 Days Ago
What Are tRFs and tiRNAs and How to Study Them?
Transfer RNAs (tRNAs) are traditional noncoding RNAs (ncRNAs) that transform genetic information from messenger RNA (mRNA) to amino acid sequence information in nascent proteins.

Published 19 Days Ago
Tools for Sorting BAM Files
Bioinformaticsis a rapidly evolving field filled with a plethora of tools for processing and manipulating next-generation sequencing (NGS) data. The performance of NGS alignment tools continues to improve, but it now takes more time to sort aligned data t

Published 19 Days Ago
What is DAP-Seq?
The biggest advantage of DAP-seq technology is that it uses in vitro expression of tagged proteins to bind the expression product to the target genome sequence, which perfectly avoids the dilemma of lack of protein antibodies that the plant research field

Published 19 Days Ago
Whole Genome Bisulfite Sequencing (WGBS) Data Analysis Pipeline
DNA methylation is an important component of epigenetics and plays an important role in maintaining normal cellular function, genetic imprinting, embryonic development, and human tumorigenesis.

Published 19 Days Ago
What is RNA m6A
RNA methylation stands as a pivotal focus within the realm of epigenetics. With a repertoire exceeding 100 distinct modifications, notable examples include methylation, hydroxymethylation, and acetylation. Among these, m6A stands as the most prevalent met

Published 2 Months Ago
Unraveling Gene Transcription: Exploring Chromatin Accessibility with ATAC-Seq
Gene transcription requires the unraveling of a higher structural part of the DNA. This part of the chromatin is called accessible chromatin region and this process is achieved mainly by the modification of chromosomal histones (especially acetylation).

Published 2 Months Ago
Long-read Sequencing Reveals Unseen Genomic Variants
A complete map of genomic variation is important to gain insight into genetic characterization and to aid in precision disease research, which can further address research areas such as evolution, agriculture, and medicine. Although short-read long sequen

Published 2 Months Ago
Introduction to the Complete Sequence of a Human Genome
The first essentially complete human genome sequence was released in 2013 as part of the Human Genome Project, which took the use of state-of-the-art DNA sequencing technology and pushed it to its absolute limits.

Published 2 Months Ago
Basics of BLAST: A Sequencing Alignment Tool
The BLAST algorithm has been fine-tuned to find these domains or shorter sequence similarity stretches. An mRNA can also be associated with a piece of genomic DNA using the local alignment method, which is usually utilized in genome assembly and analysis

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