Articles By kiko

Published 3 Years Ago
What Can We Do with NGS for Oncology?
Gene sequencing is a type of genomic testing technology. PCR, fluorescence in situ hybridization (FISH) and microarray technologies are mainly used to investigate the presence or absence of specific fragment sequences through known genes, which focuses on

Published 3 Years Ago
How Does Hi-C Sequencing Capture the 3D Organization of Chromatin?
In recent years, with the development of linear genomes, researchers have used fluorescence in situ hybridization (FISH) and chromosome conformation capture (3C) to gain a deeper understanding of the three-dimensional (3D) conformation and content of chro

Published 3 Years Ago
The Relationship Between the Gut Microbiome and Drugs Is Greater Than We Thought
Gut microbes are considered "virtual organs" that influence host health and are involved in disease research. The human gut microbiota has a large gene pool, encoding approximately 100-150 times more genes than the human genome, and contains a rich resour

Published 3 Years Ago
SNP Array, A Powerful Tool for Diagnosis and Agrigenomics Research
Single-nucleotide polymorphisms (SNPs) are a kind of DNA polymorphisms caused by single-nucleotide variants in both coding and non-coding regions, which are the most common and smallest variants. There are more than 3 million SNPs in the human genome with

Published 3 Years Ago
Long Read Sequencing Fills in the Missing Pieces of Genomics
The development of DNA sequencing technology has made it possible for human beings to explore the mysteries of themselves and other beings, while the advent of the genomics era has put higher demands on sequencing technologies. Scientific research has now

Published 3 Years Ago
CD Genomics Perspective: NGS-Based Gene Panels for Cancer Research
Tumorigenesis involves in many somatic mutations, most of which are random. Generally, hundreds of genes are thought to be associated with oncogenesis progression and have high mutation rates. Digging deeper into the cancer genome can help to understand t

Published 3 Years Ago
CD Genomics Perspective: Bioinformatic Analysis for HLA Genotyping
Human leukocyte antigen (HLA) is a 3.6 Mb segment on the short arm of chromosome 6 that contains over 200 genes. It is also known as the major histocompatibility complex (MHC), and it is the most polymorphic region in the human genome, involving diverse i

Published 3 Years Ago
RNA Sequencing Increases the Chance of RNA Biomarker Discovery
Biomarkers are defined as measurable biological characteristics that are associated with normal or pathological conditions. They possess clinical relevance, including diagnostic, prognostic, and predictive values. RNA, not only an essential part of the ce

Published 3 Years Ago
High-Throughput Sequencing Approach to Explore the Human Microbiome
A growing body of evidence now suggests that human microbial dysbiosis has a crucial role in cancer development and progression. Unlike earlier studies relying on culturing bacteria from the tissue of cancer, high-throughput sequencing methods have enable

Published 3 Years Ago
Research Progress on Application of Enzyme Technology in Food Processing
Enzyme technology usually refers to chemical reaction technology mainly through the catalytic conversion of enzymes in a limited reaction vessel. The application of enzyme technology has been distributed to all walks of life, such as manufacturing, chemic

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