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CD Genomics is aiming at providing the research community wi
Joined: November 27th, 2018
Articles Posted: 157

Articles

Published 4 Days Ago
Hybridization Capture and PCR Amplification: Comparing Two Key Enrichment Strategies in NGS
Amplicon-based approaches may be preferable for their simplified workflow and smaller amounts of required DNA. However, hybridization-based strategies are less likely to miss mutations and also perform better with respect to sequencing complexity and unif

Published 4 Days Ago
Targeting RNA Splicing: Mechanisms and Strategies
RNA splicing is a post-transcriptional modification process that occurs in eukaryotic cells. When a gene is transcribed, the initial RNA product is called pre-mRNA, which contains both coding regions (exons) and non-coding regions (introns).

Published 4 Days Ago
Comparative Analysis of Prime Editing and CRISPR-Cas9
CRISPR-Cas9 is a gene editing technology that has changed the landscape of biological research. It stands for Clustered Regularly Interspaced Short Palindromic Repeats and CRISPR-Associated Protein 9. CRISPR-Cas9 uses a two-component system consisting of

Published 4 Days Ago
Pan-Cancer Analysis Uncovers Structural Variants as Vital Contributors to Tumor Neoantigens
SVs are pervasive in roughly 94.9% of tumors and possess the potential to generate neoantigens with diminished resemblance to the body's own structures, enhancing their immunogenicity. As a result, SVs stand as a significant wellspring of neoantigens. Nev

Published 4 Days Ago
WGBS Reveals the Dynamic DNA Methylation Turnover in Plant
In some eukaryotes, DNA methylation occurs in the coding regions of genes and is called gene body methylation (GbM). Although the role of DNA methylation in transposon and repetitive DNA silencing has been well characterized, gene body methylation is not

Published 4 Days Ago
A Comparative Analysis of Prime Editing and CRISPR-Cas9
CRISPR-Cas9 is a gene editing technology that has changed the landscape of biological research. It stands for Clustered Regularly Interspaced Short Palindromic Repeats and CRISPR-Associated Protein 9. CRISPR-Cas9 uses a two-component system consisting of

Published 1 Month Ago
What Is Small Nucleolar RNAs (snoRNA) and How to Study It?
New evidence suggests that snoRNAs have a role in a variety of physiological and pathological cellular processes. snoRNA mutations and abnormal expression have been found in cell transformation, carcinogenesis, and metastasis, suggesting that snoRNAs coul

Published 1 Month Ago
What Are tRFs and tiRNAs and How to Study Them?
Transfer RNAs (tRNAs) are traditional noncoding RNAs (ncRNAs) that transform genetic information from messenger RNA (mRNA) to amino acid sequence information in nascent proteins.

Published 1 Month Ago
Tools for Sorting BAM Files
Bioinformaticsis a rapidly evolving field filled with a plethora of tools for processing and manipulating next-generation sequencing (NGS) data. The performance of NGS alignment tools continues to improve, but it now takes more time to sort aligned data t

Published 1 Month Ago
What is DAP-Seq?
The biggest advantage of DAP-seq technology is that it uses in vitro expression of tagged proteins to bind the expression product to the target genome sequence, which perfectly avoids the dilemma of lack of protein antibodies that the plant research field

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