Articles By kiko
Published 1 Year Ago
Detect Fusion Transcripts by RNA Sequencing in Screening Tumors
A fusion gene is a chimeric gene formed by the fusion of partial sequences of two genes, usually due to chromosomal translocations or deletions. These chimeric genes can form abnormal transcripts or proteins in subsequent biological processes, which can l
Published 1 Year Ago
Guide to Experimental Design: Importance and How to Design a Good Experiment
Experimental design plays a crucial role in various research areas, providing a systematic framework for conducting experiments and obtaining reliable and interpretable results. Experimental design is critical, especially when trying to avoid attrition bi
Published 1 Year Ago
Sequencing of Gut Microbiome – The Approach to Uncover Many Secrets Hidden Inside Our Gut
Our bodies have a mutually beneficial relationship with trillions of microbes currently living within the gastrointestinal tract. The microbiome is known simply as numerous species creating this population. Through improving digestion, enforcing metabolis
Published 1 Year Ago
Long-Read: Nanopore Full-Length Transcriptome Sequencing
Nanopore full-length transcriptome sequencing is an innovative technique that utilizes Oxford Nanopore Technologies' (ONT) sequencing platform to obtain comprehensive and uninterrupted high-quality full-length sequences of transcripts. This cutting-edge a
Published 1 Year Ago
The Beginner's Guide to Exosome RNA-Seq
Exosomes are small extracellular vesicles that contain RNA, proteins, and lipids. These vesicles play a crucial role in intercellular communication and have been implicated in various physiological and pathological processes. Exosome RNA-Seq is a powerful
Published 1 Year Ago
The Role of Exosome RNA in Cancer
Tumor cell-derived exosomes have important roles in reshaping the tumor microenvironment, promoting angiogenesis, metastasis and invasion, as well as regulating immune escape of tumor cells.
Published 1 Year Ago
Overview of Microbial Epigenetics
Epigenetics has been defined as the study of stable alterations in gene expression potentials that arise during development and cell proliferation, or alterations in DNA function without alterations in DNA sequence. Modern epigenetic features refer to the
Published 1 Year Ago
Nanopore Sequencing: Bioinformatics Analysis of ONT Data
Oxford Nanopore Technologies (ONT) sequencing has witnessed significant progress in recent years, becoming a key player in the genomics field. As the technology matures, so does the bioinformatics analysis of ONT data. Researchers have been diligently dev
Published 1 Year Ago
Fungi: Exploring Their Meaning, Structure, Lifecycle, and Reproductive Processes
Fungi can be single-celled or multicellular organisms. They are present in almost any habitat, but most live on the ground, instead of in the sea or freshwater, mostly in soil or plant material. In soil or on decaying plants, a community called the decomp
Published 1 Year Ago
A Primer in Biological Data Analysis and Visualization
With the development of next-generation sequencing (NGS) technologies and new sequencers, the exponential growth of biological information generated by the scientific community has brought benefits as well as new challenges to researchers. In the era of b
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