Articles By kiko

Published 5 Months Ago
Differential Gene Expression (DGE) Analysis in RNA Sequencing
DEGs, or Differentially Expressed Genes, are genes whose expression levels show significant differences between two or more conditions or experimental groups. In genetics and genomics research, gene expression refers to the process by which information en

Published 5 Months Ago
Single-Cell RNA Sequencing in Drug Discovery and Development
One of the significant advantages of scRNA-seq in drug discovery is its impact on target identification. By allowing researchers to dissect complex tissues and diseases at the cellular level, scRNA-seq enables the identification of distinct cell subtypes

Published 5 Months Ago
What Is Microbiome and How to Study It
Microbiome, commonly confused with the term microbiota, is different from the latter as microbiota is defined as the microbial members of a microbiome. While the term microbiome does not only concern the microorganisms found in a specific environment but

Published 5 Months Ago
What Is the Difference Between Aerobes and Anaerobes?
Microorganisms, specifically bacteria, have been classified into several groups depending on different characteristics such as physical appearance, culture properties, energy and nutrient requirement, biosynthetic capacity, optimal growth temperature, oxy

Published 7 Months Ago
Analytical Approaches and Applications of Whole Exome Sequencing (WES) in Oncology
Genomics has revolutionized cancer research, transforming the way we diagnose, treat, and monitor cancer. Among the powerful genetic analysis methods, Whole Exome Sequencing (WES) stands out as a cutting-edge technique that employs sequence capture techno

Published 7 Months Ago
Amplicon Sequencing Technology Unveils the Enigmas of Microbial Populations
Amplicon sequencing is a cutting-edge technique that involves sequencing PCR products or captured fragments of specific lengths, enabling the analysis of sequence variations. Among the diverse applications of this technology, the 16S rRNA gene has emerged

Published 7 Months Ago
Application of Whole Plasmid Sequencing in Analyzing Drug Resistance Genes of Klebsiella pneumoniae
Klebsiella pneumoniae is a significant causative agent of hospital- and community-acquired infections, presenting with various clinical manifestations. Notably, the rapid spread of carbapenem-resistant K. pneumoniae (CRKP) has become a global threat, lead

Published 7 Months Ago
Analysis of Differential Gene Expression (DGE) in RNA Sequencing
Differentially Expressed Genes (DEGs) are genes that exhibit significant differences in expression levels between two or more conditions or experimental groups. In genetics and genomics research, gene expression refers to the process through which the inf

Published 7 Months Ago
Applications of Single-Cell RNA Sequencing in Drug Discovery and Development
Single-Cell RNA Sequencing (scRNA-seq) offers several advantages in drug discovery, primarily through target identification. By analyzing complex tissues and diseases at the cellular level, scRNA-seq allows researchers to identify distinct cell subtypes a

Published 7 Months Ago
Prokaryotic Microorganisms and Research Methods: Exploring the Tiny World
Prokaryotes, like eukaryotes, are organisms that store their genetic information in the form of deoxyribonucleic acid (DNA). However, prokaryotes differ from eukaryotes in that their genetic material is not enclosed within a membrane-bound organelle nucle

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